MicroRNAs in Vascular Disease the beginning of a new tale

作者:ChunxiangZhang   日期:2008/5/15 0:00:00

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MicroRNAs (miRNAs) are a novel class of endogenous, small, noncoding RNAs that regulate gene expression. Mature miRNAs are 18- to 24-nucleotide(nt)-long. They negatively regulate protein expression of their target mRNAs by either translation inhibition or degradation. As a group, miRNAs are estimated to regulate at least 30% of the human genes.